Yoshihisa Yamada Selected Research

Alprostadil (Muse)

1/2022	Human Muse cells reduce myocardial infarct size and improve cardiac function without causing arrythmias in a swine model of acute myocardial infarction.
1/2022	Stem cell therapy for acute myocardial infarction - focusing on the comparison between Muse cells and mesenchymal stem cells.
12/2018	Cardiac Rehabilitation With Dynamic Exercise Increases the Number of Muse Cells in the Peripheral Blood of Patients With Heart Disease.
1/2018	Acute Myocardial Infarction, Cardioprotection, and Muse Cells.
1/2018	Mobilized Muse Cells After Acute Myocardial Infarction Predict Cardiac Function and Remodeling in the Chronic Phase.
1/2018	S1P-S1PR2 Axis Mediates Homing of Muse Cells Into Damaged Heart for Long-Lasting Tissue Repair and Functional Recovery After Acute Myocardial Infarction.

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Yoshihisa Yamada Research Topics

Disease

16	Myocardial Infarction 01/2022 - 11/2002
12	Neoplasms (Cancer) 01/2016 - 06/2002
10	Infarction (Infarctions) 01/2022 - 07/2009
8	Fibrosis (Cirrhosis) 01/2022 - 01/2010
7	Heart Failure 01/2022 - 11/2002
6	Reperfusion Injury 01/2020 - 12/2009
6	Macular Edema 02/2018 - 11/2011
5	Hypertension (High Blood Pressure) 07/2020 - 02/2008
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2018 - 06/2004
3	Left Ventricular Dysfunction 01/2022 - 09/2013
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020 - 06/2004
3	Cardiovascular Diseases (Cardiovascular Disease) 04/2019 - 01/2013
3	Heart Diseases (Heart Disease) 01/2019 - 01/2018
3	Retinal Vein Occlusion 02/2018 - 01/2014
3	Neoplasm Metastasis (Metastasis) 01/2016 - 01/2010
3	Sarcoma (Soft Tissue Sarcoma) 12/2014 - 12/2012
3	Ischemia 06/2010 - 06/2004
3	Thrombosis (Thrombus) 04/2007 - 08/2004
2	Chronic Renal Insufficiency 04/2019 - 12/2018
2	Diabetes Mellitus 01/2019 - 09/2011
2	Type 2 Diabetes Mellitus (MODY) 01/2019 - 07/2009
2	Diabetic Retinopathy (Retinopathy, Diabetic) 12/2017 - 01/2013
2	Coronary Occlusion 09/2011 - 06/2010
2	Aggressive Fibromatosis (Desmoid) 02/2010 - 07/2009
2	Osteosarcoma (Osteogenic Sarcoma) 11/2008 - 01/2006
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2022
1	Disease Progression 01/2022
1	Cysts 01/2022
1	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2022
1	Hematologic Diseases (Blood Diseases) 01/2022
1	Hyponatremia 01/2022
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2022
1	Diabetic Cardiomyopathies 01/2021
1	Sclerosis 07/2020
1	Cataract (Cataracts) 05/2020
1	Cardiomyopathies (Cardiomyopathy) 01/2019
1	Hypertrophy 01/2019
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2019
1	Body Weight (Weight, Body) 12/2018
1	Heart Valve Diseases (Valvular Heart Disease) 01/2018
1	Angina Pectoris 01/2018
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2018

Drug/Important Bio-Agent (IBA)

7	Retinaldehyde (Retinal)IBA 02/2018 - 11/2011
6	Alprostadil (Muse)FDA LinkGeneric 01/2022 - 01/2018
5	SaltsIBA 07/2020 - 01/2015
5	Glucagon-Like Peptide 1 (GLP 1)IBA 11/2019 - 06/2010
4	CreatinineIBA 07/2020 - 06/2008
4	Hypoglycemic Agents (Hypoglycemics)IBA 01/2019 - 06/2010
3	Prorenin ReceptorIBA 07/2020 - 01/2015
3	Adenosine (Adenocard)FDA LinkGeneric 01/2019 - 10/2011
3	NG-Nitroarginine Methyl Ester (L-NAME)IBA 12/2017 - 10/2010
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2017 - 02/2008
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2015 - 12/2009
2	Tolvaptan FDA Link 01/2022 - 12/2018
2	miglitol (Glyset)FDA Link 11/2019 - 09/2011
2	Therapeutic UsesIBA 04/2019 - 01/2019
2	Bevacizumab (Avastin)FDA Link 02/2018 - 01/2014
2	ReninIBA 01/2015 - 01/2015
2	KATP ChannelsIBA 10/2011 - 07/2009
2	iso-sulfan blue (Lymphazurin)FDA LinkGeneric 01/2011 - 11/2005
2	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2010 - 06/2010
2	WortmanninIBA 10/2010 - 06/2010
2	Adenosine Triphosphate (ATP)IBA 10/2010 - 06/2010
2	Nitric Oxide Synthase (NO Synthase)IBA 06/2010 - 12/2009
2	Proteins (Proteins, Gene)FDA Link 01/2010 - 01/2006
2	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 12/2009 - 01/2006
2	Matrix Metalloproteinases (MMPs)IBA 01/2006 - 01/2004
2	Adrenergic Agents (Adrenergic Drugs)IBA 06/2004 - 11/2002
1	Adenosine Monophosphate (AMP)IBA 01/2022
1	TEMPOIBA 01/2022
1	Pharmaceutical PreparationsIBA 01/2022
1	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 01/2022
1	Troponin IIBA 01/2022
1	GlycogenIBA 01/2021
1	Rifabutin (Ansamycin)FDA Link 05/2020
1	ProgranulinsIBA 01/2020
1	GlucosidasesIBA 11/2019
1	Peptides (Polypeptides)IBA 04/2019
1	Sarcoglycans (beta Sarcoglycan)IBA 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	ElectrolytesIBA 12/2018
1	Furosemide (Lasix)FDA LinkGeneric 12/2018
1	Cystatin CIBA 12/2018
1	Angiotensin IIIBA 11/2018
1	azilsartanIBA 11/2018
1	alogliptinIBA 12/2017
1	exendin (9-39)IBA 12/2017
1	Glucagon-Like Peptide-1 ReceptorIBA 12/2017

Therapy/Procedure

5	Therapeutics 01/2022 - 01/2010
4	Lasers (Laser) 12/2017 - 04/2013
3	Adjuvant Chemotherapy 12/2014 - 01/2006
3	Drug Therapy (Chemotherapy) 12/2014 - 11/2008
2	Light Coagulation 12/2017 - 04/2013
2	Vitrectomy 12/2013 - 01/2013
1	Percutaneous Coronary Intervention 01/2022
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2022
1	Cardiac Rehabilitation 12/2018
1	Sodium-Restricted Diet (Diet, Sodium Restricted) 01/2017
1	Radiofrequency Ablation 01/2016
1	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2016